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(Chest. 1956;30:456-462.)
© 1956 American College of Chest Physicians

Localized Hypertrophic Emphysema

ARTHUR W. SILVER M.D.1; JOHN W. KIRKLIN M.D.2; LLOYD E. HARRIS M.D.3; and JOHN R. McDONALD M.D., F.C.C.P4

1 Fellow in Surgery, Mayo Foundation.
2 Section of Surgery.
3 Section of Pediatrics.
4 Section of Surgical Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minn.

A case of localized hypertrophic emphysema affecting part of the left upper lobe of a child has been reported. Treatment consisted of surgical resection of the diseased tissue.

The examination of gross specimens revealed characteristic pathologic findings. The lung tissue did not collapse when the bronchi were opened as it does in the normal lung. The alveoli were dilated and enlarged but the bronchial tree appeared to be entirely normal.

A review of the literature revealed 18 cases of localized hypertrophic emphysema or a condition closely resembling it. As yet the cause of the disease is not established and various etiologic factors have been suggested. Several or none of these factors may be implicated in any particular case.






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