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A case of a malignant mesothelioma is described starting in the diaphragmatic portion of the pleura and invading the left hemidiaphragm and the peritoneal cavity. Malignant pleural tumor is a definite clinical entity even if its pathological classification remains a matter of speculation.
Persistent or recurrent discomfort from one hemithorax or one side of the epigastrium may be the initial symptom of such a growth in the absence of positive roentgenological findings.
Spontaneous pneumothorax may occur at any time during the course of this disease or may be the initial feature.
Mesothelioma must be included in the differential diagnosis of solid intrathoracic masses, persistent pleurisy with effusion, and progressive fibrothorax.
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