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(Chest. 1957;31:688-695.)
© 1957 American College of Chest Physicians

Histoplasmosis on a Small Tuberculosis Service in a General Hospital

GEORGE W. POST M.D., F.C.C.P.1; ALBERT JACKSON M.D., F.C.C.P.1; and PAULINE E. GARBER M.D.1

1 The Tuberculosis Service, Medical Service, and Pathology Service of the Veterans Administration Hospital.

1. Since mycotic pulmonary infections are now relatively more frequent, their differential diagnosis is especially important on tuberculosis services because of their clinical and radiologic similarity to pulmonary tuberculosis.

2. Two cases with histoplasmosis are reported. One had repeatedly positive sputum cultures for Mycobacterium tuberculosis, and histoplasmosis was diagnosed only at postmortem by microscopic tissue examination with PAS stain and culture of Histoplasma capsulatum from autopsy material. The other had a giant cavity on admission and progressive disease on serial chest x-rays films over a period of nearby two years. Sputum cultures were positive for Histoplasma capsulatum and negative for Mycobacterium tuberculosis. Intradermal sensitivity tests were positive with both tuberculin and histoplasmin. Complement fixation tests were negative for histoplasmosis.






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Copyright © 1957 by the American College of Chest Physicians.