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(Chest. 1957;32:544-549.)
© 1957 American College of Chest Physicians

Is Streptomycin an Ineffective Antituberculous Therapy in the Absence of Acquired Host Resistance?

EUGENE C. JACOBS M.C. U.S.A., F.C.C.P.1

1 The U.S. Army Hospital.

It is concluded from the above observations that streptomycin is ineffective in the treatment of tuberculosis prior to the acquiring of host resistance, but becomes effective as soon as acquired host resistance becomes well established.

Methods of accelerating and increasing acquired host resistance have been suggested as a means of enhancing the effectiveness of streptomycin therapy in tuberculosis. It is also possible that similar methods of accelerating and increasing host resistance could enhance the effectiveness of other antibiotic and chemotherapeutic agents in the treatment of tuberculosis, and even some other diseases.






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Copyright © 1957 by the American College of Chest Physicians.