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1 The Medical Service, Veterans Administration Hospital.
Clinical experiences with the use of Thorazine in 35 patients with bronchial asthma and/or chronic pulmonary emphysema are reported. The effect on minute volume of respiration and arterial blood gases and pH, was determined in 21 patients with chronic diffuse obstructive pulmonary emphysema.
It is concluded that the drug may be safely and effectively administered, either singly or in combination with known bronchodilator agents, in the therapy of paroxysms of bronchial asthma. In chronic pulmonary emphysema, chlorpromazine appears to be a useful adjunct, in combination with intensive therapy designed to correct pulmonary ventilation.
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