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1 The Department of Thoracic and Cardiovascular Surgery of The Latter-day Saints Hospital, Salt Lake City, Utah.
1. A method for correcting mitral insufficiency using a transvalvular polyvinyl formalinized (Ivalon) sponge has been described.
2. Experience with placement of Ivalon in the region of the mitral valve in experimental animals and in a few patients indicates that the incidence of serious complications is low. This may well be due to the ingrowth of vascular fibrous tissue and surface "endothelialization." The characteristics of the implanted Ivalon become somewhat similar to living tissue.
3. The technique, as described, appears to be well tolerated and the degree of correction of the insufficiency can be controlled within reason after the prosthesis has been placed within the heart.
4. Experience with the method is so limited that the operative mortality rate, the incidence of complications and the results cannot be estimated at the present time.
5. The early results seem to he favorable enough to justify further limited clinical application but widespread clinical use is inadvisable.
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