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1 The Departments of Medicine and Surgery, Jefferson Medical College.
1. The fall in cardiac output associated with intermittent positive pressure breathing would appear to be definite.
2. With a peak pressure setting of 20 cm. H2O, these changes do not appear to be of sufficient magnitude to effect adversely the group of patients studied.
3. Upon cessation of treatment, the recovery of cardiac output is both prompt and complete.
4. The magnitude of the changes noted, as well as their transiency, would suggest that intermittent positive pressure breathing as used in this study was associated with no deleterious effect in the uncomplicated case of advanced pulmonary emphysema.
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