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(Chest. 1960;38:51-55.)
© 1960 American College of Chest Physicians

Reversion and Reconversion Rate of Tuberculin Skin Reactions in Correlation with the Use of Prednisone

SOMCHAI BOVORNKITTI M.D., F.C.C.P.1; PRASERT KANGSADAL M.D., F.C.C.P.1; POONSRI SATHIRAPAT M.D.1; and PAIROJANA OONSOMBATTI M.D.1

1 The Department of Medicine, Siriraj Hospital Medical School.

The present report is based on 70 natural tuberculin converters who received prednisone during an antituberculosis regime. Intradermal test with 5 T.U., P.P.D. were done at 72 hour intervals before, during and after a course of prednisone.

The original statement of Boquet and Bretey (1934) 18 that there is no correlation between the intensity of the tuberculin reactions and the severity of the tuberculous infections is confirmed.

Our study has shown that with the use of prednisone in an adequate dosage and for an adequate duration the cutaneous tuberculin sensitivity in both active and inactive cases of tuberculosis could be totally inhibited. The mean reversion and reconversion rates are 13.6 ± 10.1 and 6.0 ± 3.3 days respectively.






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Copyright © 1960 by the American College of Chest Physicians.