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(Chest. 1961;39:551-556.)
© 1961 American College of Chest Physicians

The Physiologic Advantage of Oxygen During Exercise in Patients with Coronary Artery Insufficiency

EDUARDO R. PONS JR. M.D., F.C.C.P.1 and JUDITH L. BERG M.D.1

1 The Department of Medicine, Columbia University College of Physicians and Surgeons, The Presbyterian Hospital, and the Goldwater Memorial Hospital (Columbia Research Service).

1. The inhalation of oxygen at rest produced electrocardiographic changes in 14 of 22 patients with clinical coronary artery insufficiency. Elevation of the T wave occurred in seven.

2. The inhalation of oxygen during a standard Master two-step test inhibited some or all of the electrocardiographic abnormalities which occurred when the same exercise was performed breathing air, in 11 of 12 cases. In nine, there was decrease of ST segment depression when the exercise was performed with the aid of oxygen.

3. The use of oxygen during periods of exercise producing myocardial hypoxia in patients with coronary insufficiency appears to be a new approach that deserves additional physiologic study and clinical use.






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Copyright © 1961 by the American College of Chest Physicians.