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(Chest. 1961;39:609-613.)
© 1961 American College of Chest Physicians

Effect of Experimental Tuberculosis on Incorporation of C Acetate into Fatty Acids and Cholesterol

E. P.M. BHATTATHIRY Ph.D.1; T. A. VENKITASUBRAMANIAN Ph.D.1; and R. VISWANATHAN M.D., F.C.C.P.1

1 V.Patel Chest Institute, University of Delhi

Acetate utilization for the purpose of fatty acid synthesis is found to be decreased in tuberculous guinea pigs as compared to normal ones. This difference was more pronounced in the lungs than in any other organ. In vivo experiments showed this difference of acetate utilization for fatty acid synthesis. The experiments with pair fed animals receiving isocaloric balanced diet also gave identical results. No appreciable change in the cholesterol synthesis was noticed in either case.






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Copyright © 1961 by the American College of Chest Physicians.