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(Chest. 1961;39:630-642.)
© 1961 American College of Chest Physicians

Pulmonary Fungus Infections Associated with Steroid and Antibiotic Therapy

HERSCHEL SIDRANSKY M.D.1 and MAURICE A. PEARL M.D.2

1 The Department of Pathology, Tulane University School of Medicine, and Charity Hospital of Louisiana at New Orleans., Life Insurance Research Fellow, 1956-1957.
2 The Department of Pathology, Tulane University School of Medicine, and Charity Hospital of Louisiana at New Orleans., Trainee, National Heart Institute, National Institutes of Health, Bethesda, Maryland.

Twenty cases of pulmonary fungus infection due to Aspergillus, Mucor, and Candida were observed at necropsy during the past three years at Charity Hospital at New Orleans. Nineteen of them were associated with steroid and/or antibiotic therapy. The incidence of pulmonary fungus infection due to so-called "saprophytic" fungi has increased in recent years and appears to be related to the use of steroids and antibiotics in chronically ill patients. Awareness of the hazard of such infections is necessary in prevention or in diagnosis and treatment.






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