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(Chest. 1962;41:34-40.)
© 1962 American College of Chest Physicians

Circulatory Effects of the Valsalva Maneuver in Emphysema and the Influence of Ganglionic Blockade

J. J. Daly M.A.1; Frieda G. Gray M.D.1; and Rashid Massumi M.D.1

1 Cardiopulmonary Laboratory, Department of Internal Medicine, and Woodruff Hospital, Yale University School of Medicine, New Haven, Connecticut

1. The responses of the systemic and pulmonary vascular net pressures to the valsalva maneuver in patients with emphysema have been studied.

2. In a majority of patients a systemic arterial overshoot after the maneuver was accompanied by an overshoot in right atrial, pulmonary arterial, and pulmonary artery wedge net pressures.

3. In six patients the pulmonary vascular overshoots were reduced or abolished by the ganglionic blocking drug, tetraethyl-ammonium chloride (TEAC).

4. The results support the view that following a Valsalva maneuver a rise in postarteriolar resistance may contribute to the pressure overshoot in the pulmonary circulation.






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Copyright © 1962 by the American College of Chest Physicians.