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(Chest. 1962;41:68-74.)
© 1962 American College of Chest Physicians

Pulmonary Aspects of Some Toxic Experimental Space Fuels

Edward M. Cordasco M.D., F.C.C.P.1; Roger W. Cooper M.D.2; James V. Murphy M.D.3; and Carl Anderson A.A.I.T.4

1 Assistant in Medicine, University of Buffalo, School of Medicine
2 Radioisotopes Section, Baylor University Medical School (Methodist Hospital, Houston, Texas)
3 Chief, Department of General Practice, Mt. St. Mary's Hospital
4 Chief Inhalation Therapist, Mt. St. Mary's Hospital

(1) Acute diborane intoxication is associated predominantly with bronchopulmonary involvement, whereas acute decaborane and pentaborane toxicity is manifested primarily by neurologic abnormalities.

(2) Two cases of acute diborane intoxication with pneumonitis were encountered.

(3) Chronic respiratory distress was present in two patients from recurrent diborane exposure and in one patient from combined triple borane exposures. This chronic disability is most likely on a hypersensitivity basis and appears clinically as an asthmatic bronchitis. This is borne out by the obstructive ventilatory patterns demonstrated in the pulmonary function tests.

(4) The cause of the hyperventilation in one chronic patient thus far has not been ascertained.






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