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1 Department of Surgery, Tokyo National Chest Hospital,Kiyose, Tokyo
From 1948 to 1959, 2523 pulmonary resections for tuberculosis performed at the Tokyo National Sanatorium have been studied in regard to complications by sputum status prior to operation.
In the contaminated group, there was no significant difference in the proportion of complications regardless of sputum status. In the noncontaminated group, SM-resistant cases showed a higher incidence of complications compared to INH-resistant, susceptible, and "no organism" cases. In resections in patients with SM-resistant tubercle bacilli, the proportion of complications was reduced using effective drugs, that is, VM, KM and sulfisoxazole in the noncontaminated group.
It appears that in the presence of contamination at surgery and with SM-resistant tubercle bacilli, effective drugs such as VM, KM, sulfisoxazole have the most influence on the proportion of complications.
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