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(Chest. 1962;42:74-78.)
© 1962 American College of Chest Physicians

Use of Superheated Saline Aerosols as a Diagnostic Measure in Pulmonary Tuberculosis

A Preliminary Report

Gustav J. Beck M.D., F.C.C.P.1 and Krishna Nanda M.D.2

1 Instructor of Medicine, Columbia University
2 Columbia University Research Division, Goldwater Memorial Hospital

A study of the value of inhaling heated hypertonic aerosols in the diagnosis of pulmonary tuberculosis was carried out in 62 patients. Comparative observations were made on 24-hour spontaneous sputum. A total of 163 paired sputum specimens were tested.

The heated aerosol technique resulted in cultures positive for tubercule bacilli in 15 instances in which spontaneous sputum, collected during the same 36-hour period was negative, or in which no sputum was expectorated.

An analysis of the experimental data indicates that positive sputum would have been missed in only one of 163 (0.6 per cent) instances in which the heated aerosol technique was employed. With the use of the 24-hour sputum for culture, positive sputum would have been missed in 15 instances (9.2 per cent).






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