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1 Institute of Clinical Research, Middlesex Hospital
The exact nervous mechanism of dyspnea remains uncertain, but the simplest arrangement would be one in which information concerning chest volume and the pressure developed within the chest is correlated.
Alteration in the chest volume may be appreciated as a length change, perhaps in terms of the length of the muscle fibers or of the angular rotation of the ribs. Similarly, change in the intrathoracic pressure may be recognized as an alteration in the tension within the muscle fibers. If the length change is inappropriate to the change in tension, dyspnea results. This may be expressed as "length-tension in appropriateness."
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