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1 Taipei, Taiwan, China
2 Medical Department, National Taiwan University Hospital
1. The two cases of pulmonary alveolar microlithiasis reported in a family are the youngest so far recorded in the literature. One had an early phase of roentgenologic abnormalities at two years and ten months of age and developed the characteristic findings by the age of eight years when diagnosis was made by needle biopsy. The second is four years of age, and already has fully developed classic chest x-ray abnormalities, as well as congenital heart disease.
2. Regarding etiology of this condition, we are strongly in favor of the theory of an inborn error of respiratory metabolism.
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