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(Chest. 1963;44:168-173.)
© 1963 American College of Chest Physicians

The Significance of Sinus Bradycardia in Acute Myocardial Infarction

Robert F. Haden 1; Per H. Langsjoen M.D.2; Morton I. Rapoport 2; and Jules J. McNerney 2

1 Fort Sill, Oklahoma
2 William Beaumont General Hospital

Through review of the literature we have attempted to show that sinus bradycardia may occur in various anoxic states. We have also found that bradycardia is a common occurrence in experimental myocardial infarction in animals accomplished by ligating various branches of the coronary arteries.

Sinus bradycardia occurs in from 2 to 15 per cent of acute myocardial infarctions in humans. We feel there is evidence to suggest that it may possibly be a manifestation of myocardial anoxia and as such may in some cases be a prelude to cardiac standstill or ventricular fibrillation. It therefore deserves close attention and possibly treatment. In our limited experience, isoproterenol has proved effective.






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