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(Chest. 1963;44:234-250.)
© 1963 American College of Chest Physicians

Treatment of Dogs with Oxygen under High Atmospheric Pressure, after Ligation of the Descending Branch of the Left Coronary Artery

N. G. Meijne M.D.1; A. B. Bulterijs 1; G. Schoemaker M.D.1; S. J. P. Eloff M.D.2; R. de Boer 1; and A. Sutorius-Nauta 1

1 Amsterdam, The Netherlands
2 Department of Surgery, University of Amsterdam

In 20 dogs, the descending branch of the left coronary artery was ligated and the distal part cannulated in order to measure the blood flow from the ischemic area. The influence of oxygen treatment at 1 asmosphere and at 3 atmospheres pressure was studied. Backflows did not decrease at the start of oxygen treatment. The oxygen tension in the backflow blood rose to very high levels at 3 atmospheres. Several biochemical changes appeared to be influenced much more favorably by oxygen administration at 3 atmospheres than at 1 atmosphere.






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