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1 Departments of Pediatrics, Physiology and Medicine, UCLA School Of Medicine
Pulmonary function and lung volume determinations in children with congenital heart disease demonstrated significant reduction in VC and MVV. FRC and RV were increased, this being reflected in increased RV/TLC and FRC/TLC ratios. Only the group with severe pulmonary hypertension had decreased FRC and RV, but even here the relatively greater reduction in TLC resulted in increased ratios, Changes appeared to correlate better with degree of pulmonary hypertension than with specific lesion or size of shunt.
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