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(Chest. 1965;47:167-169.)
© 1965 American College of Chest Physicians

The Importance of pH and Volume in Tracheobronchial Aspiration

Nicholas D. Exarhos M.D.1; William D. Logan Jr. M.D., F.C.C.P.1; Oslar A. Abbott M.D., F.C.C.P.1; and Charles R. Hatcher Jr. M.D., F.C.C.P.1

1 Division of Thoracic and Cardiovascular Surgery, Emory University School of Medicine

1. The effect of aspiration in 71 dogs was studied using different solutions of various pH and quantity.

2. The effects were found to be directly proportional to the acidity and volume of aspirated solution. The lower pH and larger volumes produced more severe reaction.

3. A syndrome of sudden apnea and hypotension immediately following aspiration was noted in all animals except those in which saline solution was used. This could be abolished with bilateral vagotomy, but not with atropine.

[See pdf for table]

4. Attempted neutralization of low pH aspirants did not alter the usual reaction.






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Copyright © 1965 by the American College of Chest Physicians.