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(Chest. 1965;47:284-290.)
© 1965 American College of Chest Physicians

Short Term, Low Dosage Amphotericin B Therapy for Residuals of Coccidioidomycosis

Donald C. Kent MC, USN, F.C.C.P.1 and Harry F. Kendall LCDR, MC2

1 U. S. Naval Hospital, St. Albans, New York
2 U. S. Naval Hospital

This paper deals with a clinical report of four cases treated with short term, low dosage amphotericin B therapy, the total doses being limited to a total of 2 gm. or less, with rapid clearing of the pulmonary lesions, and with no residual renal toxicity noted. It appeared that this drug may have certain potentialities, some of which are as yet incompletely explored. The question thus remains unanswered as to whether one could reap benefits of value in pulmonary coccidioidomycosis by treating more cases of pulmonary involvement, by treating them earlier, and by using less drug in this low dose, short span treatment.







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