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(Chest. 1965;48:130-139.)
© 1965 American College of Chest Physicians

Laser Surgery of Malignant Tumors

Paul E. McGuff M.D.1; Ralph A. Deterling Jr. M.D., F.C.C.P.2; Leonard S. Gottlieb M.D.2; H. Dariush Fahimi M.D.2; David Bushnell M.S.2; and Fred Roeber B.S.2

1 New England Center Hospital and Tufts University School of Medicine, Children's Hospital Research Foundation, Cincinnati
2 Department of Surgery, Tufts-New England Medical Center, Mallory Institute of Pathology, Boston City Hospital, and the Advanced Development Laboratory, Raytheon Co., Wayland, Mass.

Laser energy produced by controlled fluorescence in crystals or gases possesses a number of remarkable special properties, particularly those of coherence and high power density. Laser energy is non-ionizing unlike x-ray irradiation and may produce exceedingly high power densities. Three groups of Syrian hamsters with various cell type malignant tumors were subjected to laser radiation. A specific selective destructive biologic effect which differed significantly from that caused by heat alone and x-ray irradiation was observed. The ultimate effect of laser energy on certain malignant tumors is gross dissolution of the tumor with no tumor cells observed by histologic examination.






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Copyright © 1965 by the American College of Chest Physicians.