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(Chest. 1965;48:140-144.)
© 1965 American College of Chest Physicians

Multiple Carcinomas of the Lung and Upper Respiratory Tract

Ronald J. Knudson M.D.1; Hurst B. Hatch M.D.1; Alton Ochsner M.D., F.C.C.P.1; and Francis E. LeJeune M.D.1

1 Departments of Surgery and Otolaryngology and the Section on Chest Diseases, Ochsner Clinic

Nine cases of primary epidermoid carcinoma of the lung and a second primary epidermoid cancer of the bronchus or upper airway have been presented. All patients smoked excessively. Inasmuch as the entire respiratory tract is bathed with the same carcinogen, it is not surprising to find instances of multiple primary cancers arising from the epithelium of the respiratory tract. This, we believe, offers additional evidence of the causative relationship of smoking to cancer of the respiratory tract.






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Copyright © 1965 by the American College of Chest Physicians.