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(Chest. 1965;48:225-232.)
© 1965 American College of Chest Physicians

Hematocrit, Viscosity and Coronary Blood Flow

G. E. Burch M.D., F.C.C.P.1 and N. P. DePasquale M.D.2

1 New Orleans, Louisiana
2 Department of Medicine, Tulane University School of Medicine and the Charity Hospital of Louisiana

Patients with ischemic heart disease and erythrocytosis may experience a decrease in the frequency of anginal attacks and an increase in effort tolerance following reduction of the hematocrit by phlebotomy. The clinical improvement following phlebotomy was related to modern rheologic principles based upon the shear dependance of blood viscosity.

No attempt was made to establish an epidemiologic relationship between increased hematocrit and angina pectoris. However, it was emphasized that patients with ischemic heart disease and erythrocytosis are improved clinically by reduction of the hematocrit to between 45 and 47 per cent.







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Copyright © 1965 by the American College of Chest Physicians.