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1 Instrumentation Field Station, Heart Disease Control Program, Division of Chronic Diseases, U.S. Department of Health, Education and Welfare: Clinical Instructor in Medicine, George Washington University Hospital
2 Statistician, Instrumentation Field Station, Heart Disease Control Program, Division of Chronic Diseases, U.S. Department of Health, Education and Welfare
3 Chief, Instrumentation Field Station, Heart Disease Control Program, Division of Chronic Diseases, U.S. Department of Health, Education and Welfare, Assistant Professor of Medicine, George Washington University Hospital
The intra-observer and inter-observer variation associated with clinical spirometry was statistically analyzed. The technical errors for the MEFR and MMF measurements were large enough to question their clinical reliability, especially in borderline instances.
Measurement differences between two observers, as in this study, are statistically significant. This observation has special meaning for groups engaged in epidemiologic studies. Significant inter-individual variation will diminish the quality of pooled results.
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