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(Chest. 1965;48:305-310.)
© 1965 American College of Chest Physicians

Retreatment of Drug Resistant Tuberculosis at Battey State Hospital

Raymond F. Corpe M.D., F.C.C.P.1 and Frank A. Blalock M.D.2

1 Superintendent, Battey State Hospital
2 Chief, Clinical Research, Battey State Hospital

(1) Ninety (84 per cent) of the 107 patients with drug resistant infection obtained reversal of infectiousness.

(2) Seventy per cent of the reversal of infectiousness occurred by the fourth month.

(3) Sputum conversion occurred earlier in colored than in white patients.

(4) Sputum conversion occurred earlier in younger aged than in older aged patients.

(5) The high death rate, 15 per cent, was attributable mostly to the ravages of the pre-existing disease.

(6) There was no true toxicity to ethambutol. Not one patient exhibited more than temporary blurring of the vision. This subjective manifestation was not substantiated by visual acuity testing nor eyeground observation in any instance.

(7) There was no significant correlation between sputum conversion and specific antimycobacterial titers.

(8) The bacteriologic relapse rate to date is 6.6 per cent.






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Copyright © 1965 by the American College of Chest Physicians.