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(Chest. 1966;50:627-629.)
© 1966 American College of Chest Physicians

Effect of Ultrasonic Nebulized Suspensions on Pulmonary Surfactant

Jerome H. Modell M.D., F.C.C.P.1; Samuel T. Giammona M.D.2; and Luis A. Alvarez B.S.3

1 Assistant Professor in Anesthesiology, and Director, Inhalation Therapy Service
2 Associate Professor in Pediatrics
3 Departments of Anesthesiology and Pediatrics, University of Miami School of Medicine and Jackson Memorial Hospital

Fifteen mongrel dogs were divided into three equal groups and exposed to aerosols generated by ultrasonic nebulization of distilled water, physiologic saline solution or a wetting agent tyloxipal (Alevaire) for six hours. Such exposure did not alter the normal surface tension properties of pulmonary surfactant nor the lung stability index in any of the animals tested.






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Copyright © 1966 by the American College of Chest Physicians.