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1 Medical Research Institute, Cedars of Lebanon Division, Cedars-Sinai Medical Center, and Departments of Medicine and Thoracic Surgery
A method is described for circulatory assist utilizing the Simas computerized pulsatile postsystolic augmentation system adapted and modified for veno-arterial pumping with an oxygenator-heat-exchanger. This veno-arterial circulatory assist system has been compared with arterio-arterial pumping in 74 dogs.
In shock states the benefits to regional flows and particularly to the coronary and carotid flows are much higher for the veno-arterial system.
In 27 dogs pumped during one hour's ventricular fibrillation, coronary flows could not be adequately maintained with A-A pumping, but with V-A pumping coronary flow was restored to pre-pump or higher levels (normal sinus rhythm) and the mean value was two and one-half times the control values. The myocardium was readily converted from ventricular fibrillation to sinus rhythm by cardioversion.
Clinical applications are discussed and therapeutic trials in selected cases with shock states as well as ventricular fibrillation appear to be warranted.
This article has been cited by other articles:
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J. Hager, F. Brandstaetter, O. Dietze, I. Koller, and F. Unger The Spindle Pump--A Nonpulsatile Blood Pump for Assisted Circulation J Biomater Appl, January 1, 1990; 4(3): 225 - 330. |
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