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(Chest. 1967;51:573-586.)
© 1967 American College of Chest Physicians

The Effect of Potassium on the Electrocardiogram

Clinical and Transmembrane Correlations

Michael M. Laks M.D.1 and Stephen R. Elek M.D., F.C.C.P.1

1 Division of Medicine, Cedars-Sinai Medical Center

This review has attempted to synthesize contemporary knowledge regarding potassium and the ECG. We have stressed information obtained from the transmembrane resting and action potential correlating it with ionic gradients during the four phases of the single cardiac cycle. Alterations in these events occurring during the normal, hyperkalemic and hypokalemic states have been discussed. Information regarding this subject has been culled from the procedure of hemodialysis, and measurements of MRP, MAP and arteriovenous electrolyte concentrations in mild and severe ischemic states in the dog. The relationship between serum potassium abnormalities and the ECG of arrhythmias, myocardial infarction and myocardial ischemia is discussed.







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Copyright © 1967 by the American College of Chest Physicians.