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(Chest. 1967;52:62-68.)
© 1967 American College of Chest Physicians

Hypertrophic Pulmonary Osteoarthropathy

John H. Stenseth M.D.1; O. Theron Clagett M.D., F.C.C.P.2; and Lewis B. Woolner M.D.3

1 Mayo Graduate School of Medicine (University of Minnesota), Rochester: Resident in Surgery
2 Mayo Clinic and Mayo Foundation: Section of Surgery
3 Mayo Clinic and Mayo Foundation: Section of Surgical Pathology

The records of 1,888 cases of pulmonary neoplasm operated on at the Mayo Clinic between 1953 and 1963 were reviewed, The incidence of hypertrophic pulmonary osteoarthropathy for the total group of cases, including both benign and malignant primary lung tumors as well as tumors metastatic to the lung, was 9.2 per cent. Hypertrophic pulmonary osteoarthropathy was associated with all cell types of primary bronchogenic carcinoma except the cylindromic form of bronchial adenoma and mixed malignant tumors. Detailed comparison of comparable groups of patients with and without associated osteoarthropathy revealed many similarities and very few differences. Various theories concerning the possible cause of hypertrophic pulmonary osteoarthropathy are presented, including a detailed description of the neurogenic theory favored by us.






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Copyright © 1967 by the American College of Chest Physicians.