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(Chest. 1968;53:30-37.)
© 1968 American College of Chest Physicians

Regulation and Adjustment of the Cerebral Circulation

John S. Meyer M.D.1 and John Gilroy M.D.1

1 Departments of Neurology, Wayne State University, Detroit General Hospital and Harper Hospital of Detroit and the Wayne Center for Cerebrovascular Disease

Many factors concerned in the regulation of cerebral blood flow presented in this review have been divided into extrinsic and intrinsic groups for convenience of classification. It is apparent that the total effect of these factors is: a) the modification of perfusion pressure by changes in systemic arterial pressure, or to a lesser degree, in cerebral venous pressure and b) the modification of cerebral vascular resistance, since cerebral blood flow is proportional to perfusion pressure and inversely proportional to cerebral vascular resistance. It is thus possible to express cerebral blood flow in terms of a "formula" as shown in Fig. 1.






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Copyright © 1968 by the American College of Chest Physicians.