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(Chest. 1968;53:89-92.)
© 1968 American College of Chest Physicians

Asbestos-Penicillin Induced Pleurodesis: An Experimental Study

Fakhraddin Motlagh M.D.1 and William H. Falor M.D.1

1 Thoracic Surgical Service, Akron City Hospital

In the experimental animal, a gritty paste containing asbestos powder and penicillin crystals measuring up to 1,000 micra in length (Pen-A-Brasive), effectively destroys the mesothelial lining and leads to a firm obliteration of the pleural cavity. Utilizing a thoracoscope for introduction, the method finesses a thoracotomy and has led to minimal complications. The method has a limited potential in man for the production of pleural symphysis.






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Copyright © 1968 by the American College of Chest Physicians.