Chest ACCP Career Connection
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Order Full text via Infotrieve
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Walter, J. E.
Right arrow Articles by Jones, R. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Walter, J. E.
Right arrow Articles by Jones, R. D.
(Chest. 1968;53:729-735.)
© 1968 American College of Chest Physicians

Serologic Tests in Diagnosis of Aspergillosis

Jinks E. Walter D.V.M., Dr. P.H.1 and Robert D. Jones B.S.2

1 Ecological Investigations Program, National Communicable Disease Center, Bureau of Diseases Prevention and Environmental Control, Public Health Service, U. S. Department of Health, Education, and Welfare
2 Biological Laboratory Technician, Mycoses Section, Ecological Investigations Program, NCDC

The complement fixation test was found to be both sensitive and specific for detecting antibodies to Aspergillus fumigatus. Sera from active cases of histoplasmosis, coccidioidomycosis, blastomycosis, cryptococcosis and healthy subjects failed to elicit any reactions against aspergillin. Application of the test to sera from 21 cases of aspergillosis revealed antibodies in 14 active cases only. Of 92 sera assayed for antibodies by the complement fixation and immuno-electrophoretic tests, there was approximately 92 per cent agreement between the tests. Two cases which were initially detected by the complement fixation test only subsequently developed precipitins or were proved by culture. Thus, the complement fixation test provided a means of early provisional diagnosis.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1968 by the American College of Chest Physicians.