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1 Director, Pulmonary Division, Peter Bent Brigham Hospital; Associate in Medicine, Peter Bent Brigham Hospital and Harvard Medical School
2 Instructor in Medicine, Harvard Medical School
3 Assistant in Medicine, Peter Bent Brigham Hospital and Harvard Medical School
Eleven patients with chronic obstructive pulmonary disease completed an 18-week program of exercise training with subjective and objective improvement. Increased activities of daily living were noted by these patients and substantiated by analysis of exercise diaries. Resting and exercise heart rate decreased, and maximum tolerated work load increased significantly in all patients. Alterations of physiologic measurements produced by ventilation/perfusion abnormalities or infection invalidated VEO2 as a gauge of successful training; these factors did not limit successful training.
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