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(Chest. 1970;57:530-534.)
© 1970 American College of Chest Physicians

The Loss of Tuberculin Sensitivity in Certain Patients with Active Pulmonary Tuberculosis

W. Leonard Howard M.D., F.C.C.P.1; Morris D. Klopfenstein M.D.; Wilbur J. Steininger M.D.; and C. Eugene Woodruff M.D.

1 Muskegon Northshore Hospital, Muskegon, Michigan

Through a careful determination of the tuberculin sensitivity of patients over a long period of time, a few tuberculous patients have been identified who were no longer able to react to tuberculin. Distinctive clinical and roentgenographic changes and, in some instances, the histopathologic changes associated with this deterioration in sensitivity status are detailed.




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