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1 Veterans Administration Hospital, Surgical Service and Laboratory Service, and the University of Tennessee College of Medicine, Department of Thoracic Surgery and Department of Pathology, Memphis, Tennessee
A retrospective study of ten patients with myxomatous degeneration of cardiac valves revealed two patients with "floppy valve syndrome" and eight patients with isolated myxomatous change of apparently diverse etiology. The myxomatous degeneration can be seen in a minor degree in normal valves and to a greater extent in clinical and experimental diseases of unknown etiology. The difficulties encountered in the surgical treatment of patients with myxomatous degeneration of the cardiac valves are related to the friability of the aorta and the valve annulus.
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