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(Chest. 1970;58:84-88.)
© 1970 American College of Chest Physicians

Malignant Mixed Tumor of the Lung

Frncisco Vadillo-Briceño M.D.1; William Feder M.D.1; and Jorge Albores-Saavedra M.D.2

1 Unit of Pathology, National University of Mexico School of Medicine and the General Hospital, S.S.A., Mexico City, Mexico
2 Chairman, Pathology Unit, National University of Mexico School of Medicine and the General Hospital, S.S.A., Mexico City, Mexico

A malignant mixed tumor of the lung occurring in a 67-year-old man is presented. Clinical and autopsy findings are described. By chest roentgenograms irregular calcific deposits within a large rounded pulmonary mass were demonstrated and considered to be an important diagnostic feature. Grossly the primary tumor was large, rounded with well-defined borders and calcified and non-calcified cartilaginous nodules distributed at random. Microscopically it was composed of a mixture of three different carcinomatous components (small cell undifferentiated, epidermoid and adenocarcinoma) and several mesenchymal tissues (cartilage, adipose and myxoid tissues). These latter were well differentiated and were found only in the primary tumor; their origin is unknown. The differential diagnosis with teratomas and carcinosarcomas of the lung is discussed.






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Copyright © 1970 by the American College of Chest Physicians.