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(Chest. 1971;59:113-115.)
© 1971 American College of Chest Physicians

Conversion of Atrial Flutter to Normal Sinus Rhythm after Intravenous Administration of Edrophonium Chloride

Deitrich Fleischmann M.D.1; Samuel Bellet M.D., F.C.C.P.2; and Laurian R. Roman M.D.3

1 Division of Cardiology, Philadelphia General Hospital
2 Director, Division of Cardiology, Philadelphia General Hospital; Professor of Clinical Cardiology, Graduate School of Medicine of the University of Pennsylvania
3 Cardiologist, Division of Cardiology, Philadelphia General Hospital; Assistant Professor of Medicine, Thomas Jefferson Medical College

Carotid sinus stimulation or the administration of cholinergic drugs are known to convert paroxysmal atrial tachycardia to normal sinus rhythm. In atrial flutter usually only a slowing of the ventricular response, due to decreased atrioventricular conduction, is obtained, while the atrial flutter mechanism persists. A patient is described in whom the intravenous administration of 10 mg edrophonium chloride (Tensilon) resulted in the conversion of atrial flutter to normal sinus rhythm.






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Copyright © 1971 by the American College of Chest Physicians.