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1 Assistant Professor of Medicine
2 Department of Medicine, Cardiovascular Section, University of Kansas Medical Center, Kansas City, Kansas
Central venous pressure (CVP) measurements have been used extensively in the management of critically ill patients. The value of CVP determinations was studied by determining the relationship of left atrial and right atrial pressures in 200 patients undergoing transseptal heart catheterization. All patients had mitral valve disease. The correlation coefficient of left atrial and right atrial pressure was 0.48. Low right atrial pressure (below 3 mm Hg) was seen in 18 of 91 patients with left atrial pressure 20 mm Hg or greater. In 25 patients, acute pressure changes were induced by volume expansion, pacing, or drug infusion (isoproterenol or phenylephrine). Increases in left atrial pressure frequently failed to be reflected in right atrial pressure changes. Central venous pressure may be misleading as a guide to left atrial pressure.
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