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(Chest. 1971;59:198-202.)
© 1971 American College of Chest Physicians

Endocarditis after Cardiac Valvular Replacement

J. E. Okies M.D.1; J. Viroslav M.D.1; and T. W. Williams Jr. M.D.1

1 Cora and Webb Mading Departments of Surgery, the Departments of Medicine and Microbiology, Baylor College of Medicine, and the Methodist Hospital, Houston, Texas

In 11 men and seven women infectious endocarditis developed on their prostheses following valve replacement. Staphylococcus epidermidis was the most common etiologic agent. Four survivors were treated medically with antibiotics and supportive cardiac drugs. Two required re-replacement of the prosthetic valve in order to remove the source of unremitting infection and mechanical malfunction of the valve. Twelve deaths resulted from persistent infection, systemic embolization, and unresponsive congestive heart failure. Some of the deaths might have been prevented by earlier replacement of the prosthetic valve. This should be done early in any patient with persistent sepsis, multiple systemic emboli, or a malfunctioning valve.




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A. Perez-Vazquez, M. C. Farinas, J. D. Garcia-Palomo, J. M. Bernal, J. M. Revuelta, and J. Gonzalez-Macias
Evaluation of the Duke Criteria in 93 Episodes of Prosthetic Valve Endocarditis: Could Sensitivity Be Improved?
Arch Intern Med, April 24, 2000; 160(8): 1185 - 1191.
[Abstract] [Full Text] [PDF]


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