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(Chest. 1971;59:36S-39S.)
© 1971 American College of Chest Physicians

Leukocyte Changes in the Pulmonary Circulation

A Mechanism of Acute Pulmonary Injury by Various Stimuli

J. W. Wilson Ph.D.; N. B. Ratliff M.D.; E. Mikat M.S.; D. B. Hackel M.D.; W. G. Young M.D.; and T. C. Graham D.V.M.

Similarities between the lungs of animals subjected to hemorrhagic shock, those of human patients after cardiopulmonary bypass, and those from animals subjected to nitrogen dioxide exposure have been noted. It seems clear that in all of these cases increased vascular permeability and leukocyte sequestration may play a major role in the pathogenesis of the pulmonary damage. It appears that vigorous steroid therapy may ameliorate this damage, at least in the case of hemorrhagic shock.






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Copyright © 1971 by the American College of Chest Physicians.