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(Chest. 1972;61:56-61.)
© 1972 American College of Chest Physicians

Situs Inversus Totalis and Kartagener's Syndrome in a Japanese Population

Kimiko Katsuhara M.D.1; Sadahisa Kawamoto M.D.2; Toshiro Wakabayashi M.D.3; and Joseph L. Belsky M.D.1

1 Department of Medicine
2 Department of Medicine, Atomic Bomb Casualty Commission and Japanese National Institute of Health, Hiroshima, Japan
3 Department of Statistics, Atomic Bomb Casualty Commission and Japanese National Institute of Health, Hiroshima, Japan

Eight cases of situs inversus totalis were detected in the Atomic Bomb Casualty Commission-Japanese National Institute of Health (ABCC-JNIH) Adult Health Study sample of Hiroshima and Nagasaki, Japan. The prevalence of situs inversus totalis was one per 4,100 population. This rate is about two times that reported among Caucasians. The prevalence of bronchiectasis, which is frequently noted as an associated abnormality or complication of situs inversus, showed a significant increase when compared with that of subjects in general. Study of our cases of bronchiectasis and review of literature, although not conclusive, seemed to indicate that a congenital factor was involved. Previously reported normal peripheral blood chromosome studies were confirmed.




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