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(Chest. 1972;61:95-96.)
© 1972 American College of Chest Physicians

Malignant Granular-cell Myoblastoma of the Posterior Mediastinum

William V. Harrer M.D.1 and Arthur S. Patchefsky M.D.2

1 Assistant Professor of Pathology, Clinical Laboratories, Thomas Jefferson University Hospital, Philadelphia
2 Assistant Professor of Pathology and Assistant Director, Clinical Laboratories, Thomas Jefferson University Hospital, Philadelphia

Malignant granular-cell myoblastoma is an uncommon tumor with only 13 previously reported cases. We report a 59-year-old woman with a malignant granular-cell myoblastoma in the posterior mediastinum. Histologically, the tumor shows a definite transition from benign granular-cell histology to malignant spindle-cell sarcoma. Only the spindle-cell component is noted in the metastatic bone lesion. A neural origin is proposed for this tumor.






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Copyright © 1972 by the American College of Chest Physicians.