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(Chest. 1972;61:6S-a-12S.)
© 1972 American College of Chest Physicians

Use of Extracellular Base Excess in Diagnosis of Acid-Base Disorders

A Conceptual Approach

Clarence R. Collier M.D.1; Jack D. Hackney M.D.1; and John G. Mohler M.D.1

1 Los Angeles County-University of Southern California Medical Center, Los Angeles

Various experimentally defined areas have been added to the pH - [HCO3-]p, diagram to aid in the diagnosis of steady state acidbase abnormalities. Patients found in a state of maximum possible compensation may be said to be in a physiologically compensated state. Two such areas that can be defined reasonably accurately at present are: physiologically compensated respiratory acidosis and physiologically compensated metabolic acidosis.

A derived term called the base excess of the extracellular fluid is introduced. It has theoretic advantages over existing derived terms for the quantification of the acid-base status and should be useful for diagnosis and therapy.






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Copyright © 1972 by the American College of Chest Physicians.