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(Chest. 1972;61:394-396.)
© 1972 American College of Chest Physicians

Primary Pulmonary Aspergillosis with High Fibrinolytic Activity in the Aortic Intima

M. E. Pelczar M.D.1; Pia Glas-Greenwalt M.D.1; and T. Astrup Ph.D.1

1 St. Agnes Hospital, Baltimore; The James F. Mitchell Foundation, Institute for Medical Research, Washton, DC

Frozen sections of the aorta of a patient with pulmonary aspergillosis were studied for fibrinolytic activity by the histochemical fibrin slide technique. High fibrinolytic activity, caused by a plasminogen activator, was observed along the aortic intima. This unusual observation suggests the existence of a potential for development of fibrinolytic activity in the normal, inactive aortic endothelium of man.






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Copyright © 1972 by the American College of Chest Physicians.