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(Chest. 1972;61:459-464.)
© 1972 American College of Chest Physicians

Correlation of the Ventilation and Perfusion Aspects of Chronic Obstructive Pulmonary Disease: A Review of 100 Cases

Merton A. Quaife M.D.1 and Irving Kass M.D.1

1 Section of Nuclear Medicine and Division of Pulmonary Disease, Departments of Radiology and Internal Medicine, University of Nebraska College of Medicine, Omaha

An irreversible change of the pulmonary perfusion was observed in a series of 100 chronic obstructive pulmonary disease patients studied with a pulmonary artery perfusion scan (PAPS). This perfusion involvement was greater in patients in whom the major respiratory component was pulmonary emphysema as opposed to either chronic bronchitis or bronchial asthma. A statistically significant correlation was noted between the extent of the perfusion changes, ventilatory and physical impairment of the individual. The PAPS offers an additional method for evaluating patients with chronic obstructive pulmonary disease. An original classification of the extent of the perfusion abnormalities as detected by the PAPS is presented.




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