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(Chest. 1972;61:564-567.)
© 1972 American College of Chest Physicians

Rifampin in Initial Treatment of Advanced Pulmonary Tuberculosis

Raymond F. Corpe M.D.1 and Elio S. Sanchez M.D.1

1 Battery State Hospital, Rome, Georgia

Rifampin combined with isoniazid resulted in a regimen with very little toxicity (1 percent). Both drugs were administered orally, with excellent patient acceptance. The sputum conversion analysis deemed it to be the superior regimen. This regimen did as well as either of the other two in bringing about favorable changes on x-ray films.

The main obstacle to widespread utilization of the drug is cost.






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Copyright © 1972 by the American College of Chest Physicians.