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(Chest. 1972;61:629-632.)
© 1972 American College of Chest Physicians

Ethambutol in Tuberculous Meningitis

I. D. Bobrowitz M.D., F.C.C.P.1

1 Associate Professor of Medicine, The Albert Einstein College of Medicine

Ethambutol (EMB) was present in appreciable concentrations in the cerebrospinal fluid of patients with tuberculous meningitis and after a dose of 25 mg/kg, in a majority of cases, the cerebrospinal fluid concentration was 1 µg/ml or higher. Combination chemotherapy including EMB was effective in the treatment of six of eight patients with tuberculous meningitis.




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