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(Chest. 1972;61:644-648.)
© 1972 American College of Chest Physicians

Friedreich's Ataxia in Childhood

Case Report with Possible Myocardial Infarction, Cerebrovascular Thromboembolization, and Persistent Elevation of Cardiac Specific LDH

Ehud Krongrad M.D.1 and Howard A. Joos M.D.2

1 Associate, Division of Pediatric Cardiology, Department of Pediatrics, Babies Hospital, Columbia University, College of Physicians and Surgeons, New York
2 Professor of Pediatrics, State University of New York, Downstate Medical Center; and Director of Pediatric Services Maimonides Medical Center, Brooklyn

A seven-year old Caucasian girl with Friedreich's ataxia, cerebral thromboembolism, possible repeated myocardial infarctions and severe cardiac involvement is presented. The father and a paternal uncle both died of myocardial infarction at an early age. Persistent elevation of LDH isoenzyme 5 following angina-like attacks is reported for the first time in Friedreich's ataxia and suggests continuing damage to the myocardium.






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Copyright © 1972 by the American College of Chest Physicians.